SNPs weighting file is used for constructing weighted XRM or computing SNP effect, the first column should be the SNP id, and the rest columns are the weights of SNPs, please ensure that all weights should be positive values, an example with three SNPs is as follows:
SNPid weight SNP1 42 SNP2 0.3 SNP3 100
The file should be assigned to parametric option --snp-weight
.
NOTE
If --add
is specified, additive weights should be provided, so does the flag --dom
. If both --add
and --dom
are specified, the weights of all SNPs for additive and dominance should be provided in file, the column of additive weights should be at the front of dominant weights.